Fans went wild for the Beatles, the Arts Tower became Sheffield's tallest building and the Goodwin Fountain at the top of Fargate was unveiled.
This retro photo gallery proves Sheffield didn't miss out on the fun during the 1960s, as a cultural revolution swept the world.
John Lennon is pictured backstage at Sheffield City Hall, a very different looking West Street is seen and chefs are shown cooking up a storm at Sheffield's luxurious Grand Hotel.
These images from the archives also show how much neighbourhoods across the city have changed, from the shops on West Street to Leppings Lane, in Hillsborough, Gleadless Valley and Woodseats.
33. The King Mojo Club
The King Mojo Club, on Pitsmoor Road, Sheffield, opened in 1964 and was run by Peter Stringfellow. It is pictured here in March 1966, the year before it closed. Photo: Picture Sheffield | Picture Sheffield
34. Head for heights
Thomas Bray cleans a lamp post under the shadow of the University of Sheffield Arts Tower block, in March 1969. The 62-year-old had worked for the last 22 years as lamp post maintenance man for the Sheffield Corporation. | Sheffield Newspapers
35. Attercliffe Youth Centre
Youngsters play Scrabble at Attercliffe Youth Centre, on Coleridge Road, Sheffield, in January 1969 | Sheffield Newspapers Ltd
36. Graveyard clean-up
Pictured at work clearing up the graveyard at St Thomas Church, on Holywell Road, Brightside, Sheffield, in Kuly 1969, as part of Springclean 69, are these fourth formers from Hinde House Comprehensive School, Sheffield | Sheffield Newspapers