Fans went wild for the Beatles, the Arts Tower became Sheffield's tallest building and the Goodwin Fountain at the top of Fargate was unveiled.
This retro photo gallery proves Sheffield didn't miss out on the fun during the 1960s, as a cultural revolution swept the world.
John Lennon is pictured backstage at Sheffield City Hall, a very different looking West Street is seen and chefs are shown cooking up a storm at Sheffield's luxurious Grand Hotel.
These images from the archives also show how much neighbourhoods across the city have changed, from the shops on West Street to Leppings Lane, in Hillsborough, Gleadless Valley and Woodseats.
37. Brendan Ingle
A young Brendan Ingle, who would go on to become a legendary boxing trainer, pictured with his gloves on in June 1969 | Sheffield Newspapers
38. Record-breaking knife
The Joseph Rogers Knife, now known as the Stanley Millennium Year Knife, has more blades than any other knife in the world. Sylvia Kaiser is pictured here unveiling the 1966 blade on July 10, 1966. It was made by Sheffield cutlers Joseph Rodgers & Sons in 1821, with the number of blades matching the year. More blades were added over the years, including special additions for occasions such as the 1953 Coronation and the 1966 World Cup. In the year 2000, a final 2000th silver blade was added bearing the Sheffield hallmark from the Sheffield Assay Office. | Sheffield Newspapers Ltd
39. Room for one more?
Children on a packed roundabout at Countess Road playground, Sheffield, on April 24,1962 | Sheffield Newspapers Photo: Sheffield Newspapers Ltd
40. Brothers
Peter and Geoffrey Stringfellow, the Sheffield pop music promoters with aspirations of becoming national television DJs, in September 1964. Peter would go on to achieve global fame through his nightclub empire, which started with the success of the Mojo Club in Sheffield. | Sheffield Newspapers Photo: Sheffield Newspapers