King Charles III, the Princess of Wales, who died in 1997, Prince William and Prince Harry are among those to have visited the Steel City over the years.
The late Queen and Queen Mother also visited.
We have put together a gallery looking back at some of those visits to the city over the years.
Our picture gallery shows visits over the last five decades.
13. Tea ladies
Prince Charles with tea ladies at the Royal Hallamshire Hospital - 1st November 1979 Photo: Sheffield Newspapers
14. Northern General
Princess Anne visits the Northern General Hospital Spinal Injuries unit. The Princess Royal at the occupational rehabilitation department, chats to Janice James, watched by Dorothy Topliss, seated right. Photo: Andrew Partridge (staff)
15. Princess Anne
Princess Anne visits the Northern General Hospital Spinal Injuries unit. Sisters Olivia,9 and Tasmin Taylor, 7 present the Princess Royal with a posy. Photo: Andrew Partridge (staff)
16. Princess Margaret
Princess Margaret, the Queen's sister, visits Sheffield Children's Hospital in July 1976 Photo: Sheffield Newspapers