The force recently revealed that three young women in Sheffield were the victims of injection spiking in Code on Eyre Street and Popworld on Carver Street over Halloween weekend in Sheffield.
The women, two aged 18 and one aged 19, were hospitalised but have since been discharged.
Remembering 'beautiful' and 'amazing' Blake and Tristan Barrass three years on from tragic Sheffield brothers' funeral
EuroMillions: Mystery winner from South Yorkshire has won £79,242.50 on The National Lottery
Sheffield Council employees sacked as fraud increases including theft and excessive internet use during work
Power cut Sheffield: Hundreds of homes in Hillfoot area without power ahead of 28C heatwave today
Sheffield sexual assault: Girl, 13, victim of 'serious' sexual assault in Chapeltown
There were also reports of injection spiking in Barnsley over the same weekend.
Despite police warnings, extra police patrols and officers working with pubs and clubs to try to prevent injection spiking, the force has now admitted that there were reports of more incidents last weekend.
It has not yet been revealed where the spiking is reported to have taken place or how many victims there were.
South Yorkshire Police said: “There have been some reports over the weekend of further spiking incidents across South Yorkshire. Investigations into these are at an early stage and officers are working to determine the exact nature of these incidents.
“We are continuing to work with venues to ensure they have suitable plans in place to help prevent incidents. We encourage anybody who believes they may have been a victim of spiking to report it immediately so it can be investigated.”
Sheffield MP Paul Blomfield discussed his concerns about injection spiking in the city in the House of Commons yesterday.
The latest Government figures suggest around 200 injection spiking incidents have been reported across the country.
Anyone with information on those involved in injection spiking should call South Yorkshire Police on 101.