Of course, since the two clubs last locked horns at S6 in October 2014 the Hornets spent five years in the Premier League until their relegation back to the Sky Bet Championship at the end of last season.
But what’s happened to the players who lined up for the Owls in a 3-0 defeat back in the autumn of 2014?
Let’s take a look.
5. Kieran Lee
The former Manchester United youth teamer is currently without a club after his contract at Hillsborough ended at the end of last season. The 32-year-old made just under 200 appearances for the Owls after joining the club from Oldham Athletic in 2012. Photo: George Wood
6. Joe Mattock
The 30-year-old former Leicester City youth team product made just under 60 appearances for Wednesday between 2012 and 2015. Mattock currently plays for Wednesday's South Yorkshire neighbours, Rotherham United, for whom he joined after being released by the Owls in May 2015. Photo: Chris Brunskill
7. Liam Palmer
The Worksop-born full-back, who joined the club he grew up supporting at the age of just eight, last month celebrated the 10th anniversary of his fist team debut for the Owls. The 28-year-old Scotland international has played more than 250 times for the club. Photo: Steve Ellis
8. Jacques Maghoma
The 32-year-old Congolese midfielder spent two seasons at S6, playing over 50 games for the Owls. He's currently without a club after being released by Birmingham City in the summer, although recent reports have linked him with moves to fellow Championship sides Luton Town and Wycombe Wanderers as well as League One outfit Hull City. Photo: Getty Images