The Owls are now looking to appoint their third manager of the campaign in an effort to find some much-needed stability and avoid becoming embroiled in a relegation battle towards the tail-end of the season.
Here's our rundown of SkyBet’s latest front-runners who could become the next Sheffield Wednesday manager.
9. Chris Coleman - Current odds: 7/2
Current job: Unemployed. Last job: Hebei China Fortune. Career win percentage: 31.6% (Photo by Catherine Ivill/Getty Images) Photo: Catherine Ivill
10. Paul Cook - Current odds: 1/3
Current job: Unemployed. Last job: Wigan Athletic. Career win percentage: 43.1% (Photo by Nathan Stirk/Getty Images) Photo: Nathan Stirk