From churches to pubs, nightclubs and sports venues, many notable landmarks across the city have been consumed by flames.
This retro photo gallery looks back at those sites, showing them before and after the fires struck.
Most of these landmarks were so badly damaged that they had to be demolished, while in other cases the charred shell was left standing, open to the elements.
The fires that destroyed these buildings include the largest ever peacetime conflagration in Sheffield, which broke out beside the railway tracks more than a century ago.
These nostalgic images show the lost landmarks inside and out, revealing the beautiful architecture and stunning interiors that are sadly no longer.
How many of these old landmarks do you remember?
5. Zion Congregational Church
Zion Congregational Church, on Zion Lane, Attercliffe, Sheffield, in May 1980. The church was demolished soon after a fire in 1987. | Picture Sheffield
6. Naas Curry Inn
Naas Curry Inn, on The Wicker, Sheffield, in March 1983. It was demolished in the late 1980s after a fire. | Picture Sheffield Photo: Picture Sheffield
7. Norfolk Park pavilion
The pavilion in Norfolk Park, Sheffield, in March 1984. It was later destroyed by fire, with only the stone archway surviving. | Picture Sheffield/David Cathels Photo: Picture Sheffield/David Cathels
8. The Republic
The Republic/Gatecrasher nightclub (formerly Roper and Wreakes steelworks), on Matilda Street, Sheffield city centre, in 2000. It was destroyed by fire on June 18, 2007. | Picture Sheffield/Colin Richards Photo: Picture Sheffield/Colin Richards