It is the pizza restaurant chain’s first ever festive-themed pie that includes turkey and a take on pigs in blankets, plus Cumberland sausage and crispy bacon.
Called The Festive One, it also includes Domino's signature tomato sauce and mozzarella cheese.
A large version costs around £19.99 and it went on sale on Monday, alongside a new dessert based on After Eight mints.
Melanie Howe, Domino's menu maker, said: “With less than 70 days until Christmas, we just know Brits are going to love these new festive flavours our chefs have come up with.
"They’ve combined high quality ingredients and superfan feedback to create something that’ll truly bring joy to people’s taste buds this Christmas."
A number of Star readers took to social media to deliver their verdict on the recipe.
Paul Hopwood joked: “But no gravy?”
Meanwhile, Craig Lambert said he “had this yesterday” and described it as “fantastic.”
It is not the first festive pizza on the market.
Last year, Papa John's launched a festive pizza with a red wine gravy base, and is topped with tender turkey meatballs, roasted vegetables Brussels sprouts, and finished off with a rich cranberry drizzle.
In addition, microbrewery Zero Degrees, which has branches in Reading, Cardiff, Bristol and Blackheath, south London, launched a roast dinner pizza for the festive season.
In 2020 both Lidl and Morrisons launched pigs in blankets pizzas too.
The pizza and desert are available at Domino’s across the city including the city centre, Ecclesall Road and Crookes.