From Sylvester Stallone to Sir David Attenborough and Dame Vivienne Westwood, household names have made their way to the city for all sorts of reasons.
Here are 10 memorable appearances that were caught on camera for posterity.
1. Victoria Wood
The comedian officially opened an exhibition at Sheffield Children's Hospital in 2001. Photo: Chris Lawton
2. Pablo Picasso
The painter - one of the most influential artists of the 20th century - is pictured arriving at Sheffield Midland Station in 1950 for the World Peace Congress. Photo: JPIMedia
3. Sylvester Stallone
Sylvester Stallone is seen here with Maurizio Mori in Nonna's restaurant on Ecclesall Road in 2015 - he had just appeared at Sheffield City Hall for an 'audience with' event. Photo: Submitted
4. Joan Rivers
The acid-tongued comedian launched the Sheffield Doc/Fest at the Leopold Hotel in 2010. A documentary about her career, Joan Rivers: A Piece of Work, was one of that year's highlights. Photo: Steve Ellis