The Blades will be looking to get the season off to a flyer, and get one over on a side they've failed to beat in their last five attempts, in a record stretching back to 2009.
Speaking ahead of the game, United midfielder Ben Osborn gave his thoughts on the season ahead, and said: “It's tough. (The second tier) is always tough. Obviously the other two teams that came down [Fulham and West Brom] will want a strong challenge as well.
“But we definitely want to be up there. The way we're going about things in training, the way we're looking to play and take the game to teams, shows we'll be going out more often than not to win games of football.
“The lads have really taken to the gaffer and his staff, trying to implement something a little bit different. He's certainly impressed us.
“Everyone knows his history and the lads were excited even before he started working with us.”
Meanwhile, Blades boss Slavisa Jokanovic revealed his thoughts on the side's pre-season efforts, and said: “I have to be pleased with the attitude and the determination that has been shown. The players have shown they are listening and ready to take things on board, which is good to see. That is exactly what we want.
“Of course there are things that still need work, but you must look to improve all the time. That is part of football. There are always things you can do better. That’s why attitude and personality are so important.”We’ve gathered the best of today’s transfer speculation below…

1. Baggies eye Lawrence
West Brom could be set to raid Derby County's already depleted squad, with reports suggesting the Baggies are keen on their key forward Tom Lawrence. The ex-Man Utd starlet has racked up 142 appearances in two seasons for his club (Daily Mail) Photo: Naomi Baker

2. Lilywhites snap up Iversen
Preston North End have brought Leicester City goalkeeper Daniel Iversen back to the club for another season-long loan spell. The 24-year-old impressed in the 2020/21 campaign, keeping nine clean sheets in 23 appearances. (Club website) Photo: Alex Livesey

3. Stoke sign Surridge
Stoke City have brought in Bournemouth striker Sam Surridge on a four-year deal. The 23-year-old was unable to break into the Cherries side, and spent five separate spells out on loan before sealing a permanent exit to the Potters. (BBC Sport) Photo: Naomi Baker

4. Royals knock back Laurent bid
Reading are said to have knocked back a bid for Nottingham Forest for their key man Josh Laurent. The ex-Shrewsbury Town man had a dazzling debut campaign at the Madejski Stadium, and was named his club's player of the season. (Nottingham Post) Photo: Catherine Ivill

