The Blades will be looking to get the season off to a flyer, and get one over on a side they've failed to beat in their last five attempts, in a record stretching back to 2009.
Speaking ahead of the game, United midfielder Ben Osborn gave his thoughts on the season ahead, and said: “It's tough. (The second tier) is always tough. Obviously the other two teams that came down [Fulham and West Brom] will want a strong challenge as well.
“But we definitely want to be up there. The way we're going about things in training, the way we're looking to play and take the game to teams, shows we'll be going out more often than not to win games of football.
“The lads have really taken to the gaffer and his staff, trying to implement something a little bit different. He's certainly impressed us.
“Everyone knows his history and the lads were excited even before he started working with us.”
Meanwhile, Blades boss Slavisa Jokanovic revealed his thoughts on the side's pre-season efforts, and said: “I have to be pleased with the attitude and the determination that has been shown. The players have shown they are listening and ready to take things on board, which is good to see. That is exactly what we want.
“Of course there are things that still need work, but you must look to improve all the time. That is part of football. There are always things you can do better. That’s why attitude and personality are so important.”We’ve gathered the best of today’s transfer speculation below…
5. Cottagers close in on Muniz
Fulham are closing in on a move to sign Flamengo forward Rodrigo Muniz, with a fee in the region of £8m said to have been agreed. Some reports have suggested that a delay in documents being exchanged could see Middlesbrough hijack the move. (Football Insider) Photo: Wagner Meier
6. Posh bring in Randall
Peterborough United have completed the signing of winger Joel Randall from Exeter City, for a fee confirmed to be in the seven-figure ball park. He's become the Posh's eighth summer signing in a successful transfer window for the newly-promoted club. (Club website) Photo: Jacques Feeney
7. Duo jostle for Edun
Luton Town and Peterborough United look set to go head-to-head in a transfer battle to sign Lincoln City left-back Tayo Edun. The 23-year-old, who also plays in midfielder, has previous played for Fulham and the England U20 side. (Football Insider) Photo: George Wood
8. Crowley could join Gillingham
Ex-Birmingham City man Dan Crowley could be set for a move to League One, after going on trial with Gillingham. He was part of Hull City's title winning side last season, with a solid loan spell at the KCOM Stadium. (The 72) Photo: David Rogers