Burke came off just after the hour mark of United’s defeat to Crystal Palace last weekend, replaced by 17-year-old Daniel Jebbison, and scans on his foot have shown a fracture that will keep him out of United’s clashes with Everton, Newcastle United and Burnley.
Ethan Ampadu the defender on loan at Bramall Lane from Chelsea, is also expected to miss the remainder of the season, while Sander Berge will not be risked for the next three games after picking up a niggle unrelated to the hamstring issue that kept him out since December.
“We picked up a few niggles and injuries,” Blades boss Paul Heckingbottom revealed ahead of his side’s trip to Everton this weekend.
“Burkey’s got a fracture in his foot which will put him out for the season and Sander has a niggle, so we’ll assess him and won’t take any risks. We’ve lost a couple at the minute but we’ll have to see how that goes.”
Asked how long Burke may miss, Heckingbottom added: “We have to be led by the scans on that.
“Whenever you get a fracture in the foot, there can be straightforward ones or one that need surgery and intervention. So we’ll be led by the scans.”
Ampadu hasn’t featured since April 17’s defeat at Wolves, when United lost 1-0 to confirm their relegation back to the Championship.
“Ethan has pelvic issues and has had them for a while. He’s been managing it through the season but it’s flared up and he’ll be out for the season now.
“You want everyone fit and available but we haven’t got that. We’ll roll with it, get others in the team and work hard towards the next game.
“It’s the biggest correlation ever, teams struggling always pick up more injuries.
“We’ve got a big list of injuries and significant ones, too. We’ve had a lot of surgery and it’s one of those seasons where nothing’s gone right in that respect.”