Michael Tonge, a rumoured Liverpool target at the time, scored both goals at the Bramall Lane end, after Neil Mellor had put the Reds ahead.
Liverpool turned it around in extra time of the second leg at Anfield, but it remains one of many memorable evenings under the Bramall Lane lights that season. But what happened to the United side from that evening?
1. SHEFFIELD, UNITED KINGDOM - JANUARY 27: Paddy Kenny of Sheffield United gestures during the E.ON sponsored FA Cup Fourth Round match between Sheffield United and Manchester City at Bramall Lane on January 27, 2008 in Sheffield, England. (Photo by Laurence Griffiths/Getty Images)
Kenny made over 300 appearances for the Blades. Completed a nine-month drug ban before United cashed in and sold him to QPR, who he helped into the Premier League. Now runs his own vehicle transport business and recently released his autobiography, The Gloves Are Off Photo: Laurence Griffiths
2. Phil Jagielka
Then a young player who had come through United's academy, Jagielka is back at Bramall Lane now as an experienced defender and a full England international Photo: Steve Parkin
3. Shaun Murphy, Australia
Central defender Murphy made more than 150 appearances for the club, during which time he shot to fame on the international stage by scoring the only goal for Australia in a 1-0 win over mighty Brazil in the Confederations Cup third place play-off match in 2001. He played for the club between 1999 and 2003. Photo: Alex Livesey
4. Robert Page
Robert Page made over 120 appearances for Sheffield United, many as captain. Still lives locally and moved into coaching after hanging up his boots. He later became Wales' U21 manager and stepped up to take caretaker charge of the senior team recently after Ryan Giggs was arrested Photo: x