The Ewood Park side are currently third in the table and looking to move back into the automatic promotion spots while the Blades are seventh and could be occupying a play-off position if they pick up three points.
Paul Heckingbottom will be faced with a squad of walking wounded when the time comes to select a side to face Blackburn Rovers.
His preparations have been hampered by a number of fitness issues affecting members of his squad, as the Blades continue a remarkable run of fixtures that is stretching them to the limit.
However, the United manager has also praised Wolves loanee Morgan Gibbs-White for his loyalty to the Blades after pushing for a return in January.
He said: “I really like his personality, and how he is. He’s determined to do well, determined to win, and I have to say he really played his part in coming back.
“Why wouldn’t Wolves want to keep a player like Morgan, regardless of whether he was playing or not?
“Put yourselves in their manager’s position. But Morgan wanted to play and be involved and thought he had a better chance of that with us, so he played a part in that.
“I think he’s fit naturally, but we did a lot of work with him. I don’t think he was too keen on that, because he just wants to play football, but you have to be fit enough to do that.
“You have to be conditioned and he’s gradually got better every game he has played since he came back.”
Take a look at the latest news and transfer stories from the second tier, as another busy midweek packed with fixtures continues:
1. Ferdinand explains why QPR didn’t sign striker
QPR director of football Les Ferdinand says discussions to bring in a striker did take place during the January transfer window but manager Mark Warburton was satisfied with the options already available to him (WestLondonSport)
2. Semenyo in no rush to leave Bristol City
Antoine Semenyo insists he is in no rush to move on from Bristol City despite interest from Scottish giants Celtic (SkySports)
3. Forest defender heads out on loan
Non-league side York City have confirmed the signing of 20-year old defender Sam Sanders on-loan from Nottingham Forest (Club Website)
4. On-loan Chelsea duo set for Terriers return
Huddersfield Town will be boosted by the return of Levi Colwill tonight against Cardiff City, with Carlos Corberan also revealing that fellow Chelsea loanee, Tino Anjorin, is now in the final stages of his rehab with the club (FLW)