The Owls were victorious down in the capital last weekend, beating play-off hopefuls QPR 2-0 thanks to goals from Michael Smith and Callum Paterson. As for the Hatters, they lost to Millwall in the lunch time kick-off and remain winless under new manager Matt Bloomfield.
Following last weekend's results, as well as Millwall's win against Portsmouth on Tuesday night, the table has Wednesday in 10th and Luton in 23rd. Danny Rohl's men are three points off the play-offs but Middlesbrough possess a vastly superior goal difference.
As for Luton, it's tight at the bottom with three points separating them and Pompey, but they'd need to have a three-goal swing to overtake them with a win. It's a possibility that even with a win, they might not move out of the relegation zone this weekend.
The Star has a dedicated Sheffield Wednesday WhatsApp Channel to bring the latest news, analysis and team & injury updates direct to your phone. Simply click here to join.
Shea Charles returning on loan is the only bit of business Wednesday have really done this month whereas Luton have been busy. The cheque book has been out and this week they recruited Thelo Aasgaard from Wigan Athletic for a fee in the region of £3.5m.
9. Teden Mengi - out
Suffered a knee injury in a training session in December and will be out for months. | Stephen Pond/Getty Images Photo: Stephen Pond
10. Tahith Chong - out
Missed the last three matches. He is recovering from a hamstring injury. | Alex Pantling Photo: Alex Pantling
11. Dominic Iorfa - out
Iorfa limped off the pitch in the draw with Millwall. He went down with any form of collision, and it has now emerged that he has a muscle injury. He's set to be out for eight weeks, which will keep him out until early March. | Getty Images Photo: Getty Images
12. Dominic Iorfa - out (continued)
Danny Rohl said: "For Dom it’s a shame - he will be out for eight weeks - a long, long time. "It’s a big muscle injury… It’s not nice, but it’s what it is, and we cannot change it now. "We’ll try and get him back as soon as possible, but when it’s such a big injury it takes time. "We know that Dom will need time also to get into a rhythm - we’ll see what it means for the season." | Getty Images