In-form attacker Marco Matias will miss Sheffield Wednesday's clash with Championship table-toppers West Bromwich Albion tomorrow after being ruled out of first-team contention for the next fortnight.
Matias, a scorer in two of his last three matches, has been sidelined by a hamstring injury.
"Matias is not an option. He will be out for a couple of weeks," said manager Jos Luhukay.
"It is very disappointing for Marco and the club. He is very frustrated because he has been in top form."
Two other players hit by recent injuries are fighting to be in contention to face the high-flying Baggies at Hillsborough.
Centre-half Daniel Pudil suffered a broken nose in the 2-1 win at Aston Villa on September 22 while right-sided Ash Baker limped out of last Friday's 1-1 draw against Leeds with a leg problem.
"On Daniel, we will make a decision today on whether he comes back to the team," said Luhukay, whose team are in 12th spot after losing only one of their last seven league outings.
"He is now 10 days out. He is training in full. There is maybe a risk (about tomorrow) but I will speak with our doctor and also with Daniel about whether he can play.
"Ash was fine yesterday. He trained at a low level and will do that again today. We are not sure whether tomorrow he will be 100 per cent. After training today, we will make a decision about Ash and his availability."
Matias, along with Pudil, missed the Leeds encounter and his continued absence is a blow to Luhukay
"Marco has given us high quality and has helped the team," the boss said. "In my time here, this was the best we have seen Marco play.
"He has been scoring goals and has been important for our team. He will come back but he needs a little bit of time."