The Owls have travelled to Fleetwood Town and Ipswich Town in less than a week, and a few days prior to that were up against league leaders, Plymouth Argyle, on home turf.
Moore had seven first team players missing when they drew 2-2 at Portman Road, but is expected to have a couple of them back in contention against the Shrimps come Tuesday evening.
Wednesday are in good shape at present in terms of their league position, six points clear of third place, but will be eager to try and reclaim their spot on top of the table come Saturday evening.
They face a Morecambe side battling at the wrong end of the table, and the Owls boss may be tempted to throw a little bit more caution to the wind in search of another three points.
Here’s our attempt at predicting the XI for this one: