Kieran Lee, whose contract runs out at the end of the season, has been preferred to Joey Pelupessy in the centre.
It is understood Monk has opted to change their formation from 4-4-2 to 3-5-2, with Fernando Forestieri set to line up as a left wing back for the first time in his career.
Defensive duo Moses Odubajo (hamstring) and Morgan Fox (ankle) miss out while midfielders Massimo Luongo (groin) and Adam Reach (toe) are also not involved.
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Twelve-goal top-scorer Steven Fletcher is edging closer to full training but remains unavailable for selection.
Wednesday are currently lying in 12th position in the Championship, six points adrift of the play-off placings
Owls: Dawson; Iorfa, Lees, Borner; Palmer, Lee, Bannan, Da Cruz, Forestieri; Windass, Wickham. Substitutes: Wildsmith, Urhoghide, Hunt, Pelupessy, Murphy, Harris, Nuhiu.