The pressure is building on Garry Monk as he looks to change the Owls’ fortunes, but the clash at Loftus Road is just one of several Championship matches to watch out for.
And as ever, we’re previewing all the main talking points ahead of this weekend's fixture list. Scroll and click through the pages:
1. Duo could be cut adrift
Barnsley (42) and Luton’s (41) fate could be sealed over the weekend if they fail to beat Wigan and Huddersfield Town respectively, and results go against them. Interestingly, slightly further up the table, Birmingham could be dragged into relegation trouble if they lose to Stoke. Photo: Ross Kinnaird
2. Jones making personal sacrifices
Luton Town boss Nathan Jones says he has made personal sacrifices in a bid to clinch safety. He said: “I’ve not been home in a week, I’ve not seen my month old daughter in a week which is extremely tough and if you’re a parent, especially a new parent.” Photo: Pete Norton
3. ‘Wigan is one point behind us’
Following another week of turmoil off the field - Wigan once again have a game at the end of it - but there’s limited sympathy from Barnsley boss Gerhard Struber in what could turn out to be a big relegation clash, dependent on the points deduction outcome. Photo: Jordan Mansfield
4. Boro youngster compared to PL big guns
Middlesbrough boss Neil Warnock compared Djed Spence to the likes of Nathaniel Clyne, Trent Alexander-Arnold and Aaron Wan-Bissaka ahead of the visit of Bristol City, where the youngster will wear a protective face mask after clashing Millwall's Murray Wallace in the 1-0 midweek win. Photo: Justin Setterfield