The two sides last faced each other back in 2019, when United came from behind twice to secure a 2-2 draw away from home, with Kieran Dowell and Enda Stevens both getting on the scoresheet.
The Blades are 14th in the table after 11 matches following a sluggish start to the season, but are just six point away from the play-offs due to the highly unpredictable nature of the division, which continues to produce shock results and see sides struggle to gain momentum.
Meanwhile, ex-United striker Carl Asaba has given his verdict on the club's record signing Rhian Brewster, who is still looking for his first league goal for the club after making 33 appearances since joining from Liverpool last year. Asaba said: “Listen, there’s no point in pretending it’s not been difficult for Rhian.
“He’s not scored as he would have liked and there’s the whole pressure on his head about the transfer fee so, because of that, his confidence is going to be a bit low.
“What I like, though, is how he approaches the games. He puts it all in and, even when he’s been asked to go out wide, he gives everything. He just tries to do his job. Seriously, if we stick with him then in two or three years time I think everyone is going to be mighty glad we did.”
Take a look at the latest stories from the second-tier, as the anticipation for this weekend's action starts to build:
1. Ashley eyes Rams deal
Ex-Newcastle United owner Mike Ashley is rumoured to be lining up a swoop for Derby County, following the £305m sale to a Saudi-led consortium. The Rams are currently in administration, and are rock-bottom of the table following an 11-point deduction. (Mirror) Photo: ANDREW BOYERS
2. Sako set for Championship move
Ex-Wolves and Crystal Palace star Bakary Sako looks to be be close to completing a move to the second tier, with a currently unnamed Championship side set to snap him up this week. He was last on the books at Cypriot side Pafos. (The Sun) Photo: BEN STANSALL
3. Man Utd tipped to sign ex-Blues star
Manchester United have been named as the front-runners to sign Borussia Dortmund youngster Jude Bellingham, as interest continues to grow in the £80m-rated England international. He joined the German side from Birmingham City last year. (Mirror) Photo: INA FASSBENDER
4. Beech loses Carlisle job
Carlisle United have parted company with manager Chris Beech, after a poor start to the season that sees the side currently 22nd in the table with just two wins from 11 games. He featured for the likes for the likes of Blackpool and Huddersfield during his playing career. (Club website) Photo: Jan Kruger