Here, our Blades writer James Shield picks out what he believes will be the line-up at the Madejski Stadium
1. Dean Henderson
Dean Henderson replaced Michael Verrips in the game against Fylde and stayed in the tema against Millwall Photo: Richard Heathcote
2. Panos Retsos
Panos Retsos could make his Blades debut at Reading Photo: Simon Bellis
3. John Egan
John Egan is yet to play in the FA Cup this season Photo: Simon Bellis
4. Jack Robinson
Jack Robinson's only appearance so far came as a substitute against Millwall in the cup Photo: Robin Parker