While the Blades are flying high in the Premier League, their opponents are in danger of slipping into the second tier relegation scrap in the coming weeks. Here's a look back at the last five fixtures between the two sides, in a fixture which has always been rich in goals and drama over the years.
5. Reading 4-0 Sheffield United - January 2013
Yep, the last time the two teams met in the FA Cup, United got thrashed. To be fair, Reading were in the Premier League, while the United were in League One. Ex-Blade Mikele Leigertwood scored a scorcher in the four-goal rout. (Photo credit: ADRIAN DENNIS/AFP via Getty Images) Photo: ADRIAN DENNIS