From the chastening 4-1 defeat at Coventry City on Saturday, Paul Heckingbottom has recalled Iliman Ndiaye in place of Conor Hourihane.
An already-young bench has been shuffled to include striker Will Osula and defender Nickseon Gomis, as well as 17-year-old Oli Arblaster.
Meanwhile, Blackpool make two changes with former Blade Gary Madine in their starting XI as well as ex-Wednesday man Jordan Thorniley.
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Blades: Foderingham, Osborn, Gordon, Egan, Robinson, Norrington-Davies, Norwood, Berge, Ndiaye, Gibbs-White, Sharp.
Subs: A. Davies, Hourihane, Lopata, Osula, Jebbison, Arblaster, Gomis.
Blackpool: Grimshaw, Sterling, Ekpiteta, Thorniley, Connolly, Husband, Stewart, Dougall, Bowler, Hamilton, Madine.
Subs: Moore, James, Robson, Kirk, Dale, Yates, Lavery.