With skipper Richard Wood serving a ban following his red card in Friday's defeat at Millwall, Warne is sweating on Clark Robertson and Matt Olosunde.
Both men have been nursing hamstring injuries and the Millers were due to assess them after Sunday's training session.
“Olosunde is a little bit sore in his hamstring,” Warne said.
“He hasn't pulled anything but just has a bit of awareness of his hammy. Whether he will be available on Monday, I don't know.
“The same with Robbo. Robbo should train on Sunday. They were both missing and when you have your centre-half and skipper sent off the fitness of your defenders becomes more pertinent.”
Warne could do with as strong a team as possible against the Chairboys, who arrive in South Yorkshire propping up the division.
They beat Blackburn on Good Friday to enhance their own survival chances, but in reality this is a game the Millers have to win if they are to beat the drop.
Warne is trying to alleviate the pressure by insisting no game is more important than another.
“It's a big game. I've said we need four or five wins from 12 games, which isn't going to be easy,” he said.
“Friday was an opportunity and we didn't take it. Monday is an opportunity.
“If we don't take that, it goes on to the next game. I don't regard any game as more important than any other. “We just need those wins. If we don't win on Monday our season isn't over and if we do win on Monday our season isn't over then either.
“We just have to keep going. We need to patch them up and get them ready for Monday. There's a lot to be happy about after Millwall. Just not the result.”
Dominic Gape is a doubt for Wanderers.
The midfielder suffered a calf injury in the 1-0 win over Blackburn and the club are awaiting news on the extent of the damage.
Winger David Wheeler could return after missing out against Rovers.
Jordan Obita is the only definite absentee with an ankle injury.