Barnsley boss Danny Wilson tastted victory in his 1000th game as a manager as the Reds hosted Leyton Orient at Oakwell.
Wilson became only the 24th manager to have achieved the magical milestone as his team looked to claim their first league win for a month.
Defender Reece Brown, the brother of former England and Manchester United professional Wes, was dropped to the substitute’s bench, with Lewin Nyatanga restored to the starting line-up.
And there were places on the bench for Marcello Trotta, the Fulham loan striker, and promising youngster Rhys Oates.
Shaun Batt had the first chance for Orient, but he curled a left-foot shot wide of the target after six minutes.
Two minutes later, Dale Jennings whipped in a delightful cross for Kane Hemmings, but the striker volleyed wide from a good position.
The Reds went ahead when Hemmings cut the O’s defence in half with a wonderful pass and midfielder Conor Hourihane cooly rounded keeper Adam Legzdins and slotted home to give the Reds a deserved lead.
Midfielder James Bailey rifled well over with an ambitious shot from the edge of the box and, on 35 minutes, Berry had to go off for a couple of minutes for a head injury. He returned sporting a new shirt and shorts because of blood on his old set, as well as a big white head-band to prevent the cut opening up further
Devante Cole put the Reds 2-0 up with a smart finish after 38 minutes. Jennings played him in with a smart pass and the Manchester City loan marksman fired between the legs of the advancing Legzdins.
In the second half Hemmings cut inside and blasted high and wide with a left-foot shot, and The O’s made their third and final substitution of the afternoon as they switched their formation to find a way back into the contest.
Berry was denied the Reds’ third goal when his point-blank volley expertly saved by Legzdins while at the other end, Barnsley keeper Ross Turnbull parried a powerful drive from Cox.
Turnbull was shown a straight red card for a handball outside his area. Jobi McAnuff’s through-ball caught the Reds’ defence cold and Batt’s touch completely decided Turnbull. Referee Mark Brown had no choice but give the keeper his marching orders, but Shane Lowry wasted the resulting free-kick as he blasted well over.
Lowry had a left-foot shot deflected for a corner in the fourth and penultimate minute of injury-time
Barnsley: Turnbull, Holgate, Ramage, Cranie, Nyatanga, Berry, Bailey, Hourihane, Jennings, Cole, Hemmings.
Subs: Brown, Treacy, Davies, Digby, Oates, Trotta, Lita.
Leyton Orient: Legzdins, Omozusi, Lowry, Cuthbert, Sawyer, Pritchard, Wright, Vincelot, McAnuff, Plasmati,. Batt.
Subs: Baudry, Cox, Mooney, Lee, Agyemang, Dossena, Woods.
Referee: Mark Brown (East Yorkshire)