But while these institutions may have physically disappeared, many of us still remember them. From the strange nights hosted at Josephine's to the mecca of all toy shops, Redgates, we take a look back at the treasures the city has lost over the years.
1. Redgates Toy Shop, closed 1988
Redgates Toy Shop was regarded as one of the best outside of London and was a big favourite with the city's children. It had several locations, including one temporary move to Ecclesall Road after being bombed in the Blitz.
Photo: Nancy Fielder
2. Odeon Cinemas, closed 1971 and 1994
Though Sheffield has one Odeon remaining at Arundel Gate, two other historic Odeons in Flat Street and Burgess Street have been lost to the ages.
Photo: Sheffield Newspapers
3. Gatecrasher One, closed in 2007
Gatecrasher One was a legendary Sheffield nightclub that caught fire in 2007, leading ultimately to the demolition of the building.
Photo: Wikimedia Commons
4. Roxy Disco, closed late 1990s
Roxy disco was a legendary spot for pop-loving revellers in the 80s and 90s, with stars like Kylie Minogue and Jason Donovan among the club's star-studded guests. It closed in the late 90s and the site is now home to the O2 Academy.
Photo: Dean Atkins