Burglars are being hunted after holidaymakers returned to Sheffield to find that their home had been raided.
They arrived at their home in Old Retford Road, Handsworth and found that the door lock had been forced to gain entry.
A safe, containing cash and foreign currency, was missing.
The occupants discovered the break-in yesterday, after going away over the weekend.
A South Yorkshire Police spokesman said: "If anyone is planning a holiday please try your best to make your home look lived in.
"Consider asking a neighbour to put your wheelie bin out on collection day, drawing curtains or closing gates.
"Houses in darkness draw attention to themselves. Consider placing lights on timers. Ensure security lighting and alarms are working and set."
The force has also issued advice to residents with safes in their homes.
The spokesman added: "If using personal safes at home secure these to something solid, sturdy and immobile."