Here's ten key moments that have defined United's challenge for promotion so far this season.
Summer signing McGoldrick got the Blades off the mark with their first win of the season against QPR. The win was the first of four on the bounce in the league.
Oliver Norwood might have missed a penalty in the shoot-out in Sheffield United's EFL Cup defeat to Hull City, but the midfielder certainly made an impact on his Blades debut and looks to be one of the best signings of the summer.
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Hailed as the best performance many Blades fans had seen at Bramall Lane for years, the 4-1 win was a sign that Chris Wilder's tactics just might help United to the Premier League this season.
The Blades went to Blackburn in a mid-week match in the hope of ending Rovers' impressive 25-match unbeaten home run and a brace from captain Billy Sharp did just that to move United level on points at the top of the league.
The Blades banished the memory of losing to Nigel Adkins' side in the EFL Cup earlier in the season to grind out a 1-0 win. David McGoldrick was on target from the spot to send United top and the Tigers bottom of the league.
The deadly strike duo of Sharp and McGoldrick were in action again as United fought back from behind to win their second 3-2 win on the bounce.
Billy Sharp's first hat-trick of the season as United thumped Wigan 4-2 at Bramall Lane.
A key moment off the pitch came just before the Sheffield derby as Chris Basham signed a new contract to stay at Bramall Lane until the end of the 2020/21 season.
Touching pre-match tributes from both Sheffield United and Sheffield Wednesday to mark 100 years since the end of the First World War was another off-pitch highlight as the city united in memory of its fallen heroes.
David McGoldrick penalties have bookended this list, but his miss in the Sheffield derby was the deciding factor to ensure the visitors left with a point at Bramall Lane last weekend. Will the Blades bounce back with a win in their next league match?