Founder Hugh Facey launched GLIDE House on Attercliffe Common at a ceremony attended by scores of staff.
The firm converted the former Jaywing headquarters, also known as Players’ Cafe and originally Carbrook County School, built in 1874.
Mr Facey said: “We had been looking for somewhere for five years. I was just driving along when I saw the ‘for sale’ sign. I came in and hated the mezzanine and pillars. But when I came a second time I thought, ‘this is it!’
Rt Revd Jack Nicholls, a former Bishop of Sheffield, conducted the official opening.
He said: “I think Hugh Facey will be on the front row in heaven when the time comes.”
Gripple makes wire joiners and has hit £60m turnover for the first time.