Trouble broke out on Willoughby Street, Page Hall, at around 4.30pm on Sunday.
A Willoughby Street resident – who did not want to be named – told The Star: “It was a massive brawl on the street for all to see.
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“I’d say there were around 50 people involved – it was ram-packed, utter carnage.
“There was so much shouting and screaming – I have no idea what it was all about but it looked really bad.
“The street looks a mess.”
He added: “Police came eventually and shouted that orders were in place and told everyone to go home.
“I’d say it all lasted around 20 minutes.”
Police have yet to comment on the latest incident – which comes after disorder on Willoughby Street during the early hours of New Year’s Day.
South Yorkshire Police said a 37-year-old man suffered injuries to his wrists, a 12-year-old girl was found unconscious and a three-year-old girl suffered minor injuries.
Officers arrested five men, all in their 20s, and they have all been bailed pending further enquiries.
The Willoughby Street resident added: “This can’t keep going on – it’s not good at all.
“I think a curfew needs to be brought in to try and bring some calm and order to the street.”
A new police team was recently set up to tackle issues in Page Hall.
Officers have turned an empty house on Robey Street into a police base in a bid to deter trouble and to have staff on hand to respond to incidents and to get to know the community better.
When the team was launched, Sergeant Tony Cartlidge said: “For me, the most important thing is having my officers out there, on the streets, in people’s faces.
“It’s about spending as much time as a shift allows, speaking to people, stopping vehicles and using enforcement where necessary.
“I am ensuring the team spend as much time on the beat as possible and getting to know their community; that is where the greatest gains can be made.”