Police are currently at the scene on West Street, close to the traffic lights outside Sundaes Gelato, and the road has been closed due to what is believed to be an abandoned vehicle – however, this has not been confirmed and the circumstances remain unclear.
Officers at the scene say it may have been used in a crime and they are currently waiting for a tow truck.
A tram is stuck behind the abandoned vehicle and has reportedly been in situ for 50 minutes.
As a result of the incident, trams are unable to run between Cathedral and Shalesmoor.
Stagecoach Supertram said: “Due to a police incident blocking West Street trams are unable to serve the city centre and are operating from Meadowhall and Gleadless Townend to Cathedral or from Middlewood/Malin Bridge to Shalesmoor.”