The fire broke out in a property in Sackville Road, Crookes yesterday, with fire crews being called to the scene at around 1.46am on Saturday, November 30.
The man was sadly pronounced dead at the scene.
South Yorkshire Police have not yet confirmed the identity of the man, and the investigation into his death is continuing today.
Yesterday, a spokesman for the force said his death was being treated as ‘suspicious,’ adding that two men, aged 35 and 38, and two 19-year-old women have been arrested on suspicion of murder.
“An investigation is underway after a body was discovered at an address in Sheffield this morning.
“Officers were called to the property on Sackville Road in Crookes at around 1:30am to reports of a fire. On attending the scene, police found the body of a man.
“At this time, the man’s death is being treated as suspicious and enquiries are ongoing to ascertain the exact circumstances surrounding his death.
“Two men aged 35 and 38, and two 19-year-old women have been arrested on suspicion of murder,” the spokesman said.
The force have been asked to provide an update on whether any of the four people arrested yesterday have been charged and if they remain in custody today.
A spokesman for South Yorkshire Fire and Rescue said: “Firefighters from Central and Rivelin were called to the incident at 1.46am and found a fire on the first floor of the property.
“Despite their best efforts the casualty was pronounced dead at the scene.
“This is a tragic incident and our thoughts are very much with the man’s family and friends at this sad time.
“A full investigation into the circumstances surrounding the fire is now underway in conjunction with South Yorkshire Police.”
Neighbours said they did not know the man, but were saddened to learn of his death.
Anyone with information is asked to call police on 101, quoting incident number 81 of November 30.