This year the charity is asking people to either host a virtual or socially distanced coffee morning.
However, we have dig out some great pictures of you enjoying a cuppa and a cake from previous coffee mornings.
See who you can spot in these pictures which go all the way back to 1998.
Want more Sheffield retro? Meadowhall shoppers from yesteryear
A message from the Editor:
Thank you for reading this story. The dramatic events of 2020 are having a major impact on our advertisers and thus our revenues.
The Star is more reliant than ever on you taking out a digital subscription to support our journalism. You can subscribe here www.thestar.co.uk/subscriptions for unlimited access to Sheffield news and information online.
Every subscription helps us continue providing trusted, local journalism and campaign on your behalf for our city.
Thank you
Nancy Fielder, editor
1. Cup and saucer time
Sheffield NatWest Managers Sue Waterhouse and Ian Clay handed over a cheque for £610.96p to Derek Dennis of the Macmillan Caner Relief after a coffee marathon in 1998 Photo: Roger Nadal
2. Cheers!
The Chesterman Unit of the Northern General Hospital took part in the World's biggest coffee morning in aid of Macmillan Cancer relief in 1999 pictured are Julie Broadhead, Cheryl Drake, Stefan Pietnik, Sue Batten, Lorna Wattan, Tracy Unwin, Claire Weiss and Louise Jepson Photo: Barry Richardson
3. Eyes down
Ten-year-old youngsters Amy Drury (left), of Branton, and Emily Cattrall, of Auckley, pictured at their fund-raising coffee morning at in 2001 Photo: Steve TAylor
4. More tea councillor?
Richard Caborn at the Sheffield Town Hall secretaries fundraiser for Macmillan Cancer Relief's biggest coffee morning. Seated Councillors Jan Wilson and Pat Midgley. Standing left to right, Kate Sheldon, Marilyne Fisher and Helen Zefi pictured in 2002 Photo: Dennis Lound (Staff)