Public Health England figures recorded in the seven days to November 25 highlights the 12 areas across the city which has an average infection rate of more than 250 cases per 100,000 people.
It comes as Sheffield and the whole of South Yorkshire are set to enter Tier Three lockdown tomorrow (Wednesday, December 2) as national restrictions end.
Find out where the neighbourhoods in and around the city with the highest case rate are below.
Images are for illustrative purposes only and are not linked to the data in the article.
In these confusing and worrying times, local journalism is more vital than ever. Thanks to everyone who helps us ask the questions that matter by taking out a digital subscription or buying a paper. We stand together. Nancy Fielder, editor.
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9. Richmond and Stradbroke
There was an average of 271.8 infections per 100,000 in the seven days to November 25 in Richmond and Stradbroke. Photo: Google
10. Birley
In the week ending November 25, Birley had an average of 262.5 infections in every 100,000 people. Photo: Google
11. Intake
Intake had an average of 255.2 infections in every 100,000 people in the seven days to November 25. Photo: Google
12. Arbourthorne
There was an average of 252.3 infections per 100,000 in Arbourthorne in the week ending November 25. Photo: Google