Baljeet Singh Kharia, owner of convenience store Singhâ€™s Premiers, donated the selection boxes as a gift to the children who will not be at home this Christmas.
Members of the Singhâ€™s team visited the hospital on Friday, December 14 to hand over the gifts.
Mr Kharia said: â€œAs a business, we believe supporting our community helps us work harder and achieve more as one.â€
The selections boxes are going to be given out to the children on Christmas Day.
Donna Webster and Katie Farrell, members of the hospitalâ€™s charity/play team were overwhelmed with the donation.
Mrs Webster said: â€œThis is the first donation of selection boxes we have received, they will be given out on Christmas day by Santa.â€
The Childrenâ€™s Hospital was aware that it was receiving a donation but staff did not know the size or content of it.
Singhâ€™s has also donated large amounts of food to the Burngreave food bank to â€˜raise awareness and make it a great Christmas for the less fortunate.
The company also urged people to do moreÂ this Christmas for the less fortunate.