Expansion of the Top 100 Manufacturers rankings to take in the whole of the Sheffield City Region has resulted in the introduction of two new geographic areas to supplement the existing town and city-based divisions.
North Derbyshire brings together businesses in towns like Matlock and Alfreton, but excludes Chesterfield, which continues to have its own separate ranking.
Meanwhile, North Nottinghamshire brings in Worksop and Newthorpe.
Topping the North Derbyshire rankings of the most profitable manufacturers is Radius Systems, which makes and installs plastic pipes and fittings for the gas, water and sewage sectors and ducting for telecoms services.
Radius was founded 44 years ago and has factories in Derbyshire and Northern Ireland and was acquired by its management in 2008 from former Finnish parent group Uponor.
Earlier this year it was acquired by Polyplastic, the leading European supplier of thermoplastic compounds and polyethylene piping systems for infrastructure markets.
Polyplastic is Russia’s largest plastic producer, with 12 plants in Russia, Belarus, the Ukraine and Kazakhstan.
Since Polyplastic took control, Radius has itself been buying up businesses.
In June, it bought the assets of the Dorset-based Subterra pipeline repairs business whose services include spray coating metal pipes and relining damaged pipes.
Only last month it bought Aeon Group Holdings, one of the leading global manufacturers of valves for the fire protection, gas, water and oil exploration and transportation sectors, which operates from facilities in the UK, Dubai and Poland.
Second-placed HJ Enthoven is the largest single site producer of recycled lead in Europe and part of the world’s largest lead group, Quexco Inc, based in Dallas in the US.
Enthoven makes around 75,000 tonnes of lead products at its Darley Dale plant each year.
The company supplies a range of lead antimony and calcium alloy ingots and continuosly cast lead calcium and lead calcium tin alloy strip for making vehicle, traction and standby batteries.
It also supplies lead-based products to cable makers, the construction industry and industry at large and recycles polypropylene for use in sectors that include housing, horticulture, electrical and civil engineering, leisure and automotive.
North Derbyshire’s third most profitable manufacturer, MMD, has grown into a worldwide organisation that makes materials processing equipment since it was founded in 1978.
Products include feeders that carry raw materials to crushing plants and “sizers” that reduces minerals down to the right size for specific construction, industrial and energy applications.
Fourth placed Sapa Profiles is the world’s leading producer of extruded aluminium profiles, with plants in Cheltenham in Gloucestershire and Redditch in Worcestershire, as well as Tibshelf in Derbyshire.