Retail and hospitality have been hit especially hard because of changing consumer behaviour and lockdown measures.
Here are 11 shops, pubs and restaurants in Sheffield that have either closed entirely or are yet to reopen since restrictions were eased earlier this summer.
5. Aagrah, Crystal Peaks
While Aagrah's curry house at Leopold Square in Sheffield city centre has reopened, its site at Crystal Peaks has permanently shut. Photo: Google
6. The Devonshire Cat
In June the Abbeydale Brewery announced that it would not be reopening The Devonshire Cat pub on Wellington Street. Photo: JPIMedia
7. The Old House
The majority of True North Brew Co's venues have reopened but some are still to come - The Old House, on Devonshire Street, is expected to reopen in September according to a recent job advert. Photo: Chris Etchells
8. Bistrot Pierre
French-style bistro chain Bistrot Pierre has permanently closed its restaurant on Ecclesall Road as part of an administration deal. Photo: Google