Sheffield Wednesday (8) v Derby (7)
Latest signing Stevie May is poised to make his Sheffield Wednesday debut. May, 21, signed from St Johnstone for £800,000 last weekend and missed the midweek Capital One Cup win against Notts County through suspension.
Boss Stuart Gray must decide which of his strikers to leave out if he opts to start with May.
Gary Madine and Atdhe Nuhiu were both on target on Tuesday night.
Midfielder Jeremy Helan (groin/stomach) is back in contention and Kamil Zayatte (ankle) could make his first start in over nine months, but defender Lewis Buxton and striker Caolan Lavery (both knee) are still out.
Derby head coach Steve McClaren must choose between Jake Buxton and Zak Whitbread to partner captain Richard Keogh at the heart of the Rams’ back line.
Whitbread played the full 90 minutes alongside the Republic of Ireland international during Monday night’s 2-0 Capital One Cup victory over Carlisle.
Buxton, who started the opening game of the Championship campaign at home to Rotherham despite spending much of the build up nursing a hip injury, was not risked at Brunton Park, having come through the full match against the Millers just 48 hours earlier.
Leon Best and Omar Mascarell will be looking to earn their first starts following their recent arrivals from Blackburn and Real Madrid respectively.
Last season: Sheffield Wednesday 0 Derby 1 Derby 3 Sheffield Wednesday 0
Top scorers (all competitions): Gary Madine, Atdhe Nuhiu & Giles Coke (Sheffield Wednesday) 1; Jeff Hendrick (Derby) 2.
Match odds: H 2-1 A 5-4 D 11-5
Referee: Scott Duncan (Tyne & Wear)