Table-topping Brighton head to Hillsborough but Sheffield Wednesday have their eyes on breaking into the top six.
This evening to can follow all the action from Sheffield, as well as Rotherham United's game away to Middlesbrough on Matchday Live with team news, pictures, video, match updates, opinion and reaction.
For more on Owls v Brighton:
Match Guide & Betting - Sheffield Wednesday v Brighton
Forestieri is simply the best says Owls team mate
Carvalhal bids to give Owls security
VIDEO: The Star's Wednesday writer Dom Howson on Sheffield Wednesday v Brighton
Pudil says Owls can follow in Hornets' footsteps