The 27-year-old was also warned as to his future conduct after admitting repeat breaches of the regulations. He has the right to appeal.
An FA statement read: “Stoke City’s Cameron Jerome has been fined £50,000, subject to any appeal, following an Independent Regulatory Commission hearing.
“Jerome, who was also severely warned as to his future conduct, admitted a number of breaches of te FA’s Betting Rules and requested a personal hearing which took place on Tuesday.”
Jerome’s charge was issued on Monday of last week. There has been no suggestion from the FA that Jerome has gambled on games in which he or Stoke were involved, or that he is in any way involved in match-fixing.
The former England Under-21 international joined Stoke from Birmingham in August, 2011.
He was in the Owls’ youth set-up but was lured away by Middlesbrough. Jerome has also been linked with Wednesday in more recent times, when the club have been in the market for a striker. He worked under Dave Jones at Cardiff.
Jerome was the second Premier League player to be charged under betting rules in recent months, following Tottenham midfielder Andros Townsend in June.
Townsend withdrew from England’s squad for the Under-21 European Championship and was subsequently banned for a month, with a further three-month ban suspended, and fined £18,000.
Accrington managing director Robert Heys has also been charged with betting offences.