Manchester United midfielder Jesse Lingard is available to face Sheffield United in the FA Cup on Saturday after he overcame a hamstring injury.
Adnan Januzaj, who was recalled from his loan at Borussia Dortmund on Thursday, is not fit enough to play, but Will Keane may feature following his return from a temporary spell at Preston.
READ MORE: All the news from Bramall Lane ahead of the clash between Sheffield United and Manchester United
Antonio Valencia (foot), Luke Shaw (leg), Marcos Rojo (shoulder) and Phil Jones (ankle) are out while Ashley Young is likely to be rested as manager Louis van Gaal says the winger is "in the red zone" in terms of his fitness.
Provisional squad: De Gea, Romero, Varela, Darmian, Borthwick-Jackson, Smalling, Blind, McNair, Schneiderlin, Schweinsteiger, Carrick, Herrera, Fellaini, Depay, Lingard, Powell, Mata, Young, Pereira, Martial, Rooney.