Owls goalkeeper Keiren Westwood has pulled out of the Republic of Ireland's squad ahead of their European Championship 2016 play-off first leg against Bosnia-Herzegovina on Friday.
The 30-year-old has withdrawn from the squad after his pre-existing ankle injury flared up in training at the FAI National Training Centre today.
It is understood Westwood, Wednesday's reigning player of the season, had another injection in his ankle after the Championship's club defeat at Charlton Athletic last weekend.
Now Westwood faces a race against time to be fit for the Owls' meeting with Huddersfield Town a week on Saturday.
Charlton Athletic goalkeeper Stephen Henderson has been drafted into the squad as a replacement.
With experienced shot-stopper Shay Given also sidelined by injury, Darren Randolph is set to get the nod in between the sticks for the Republic ahead of David Forde.