Prime minister David Cameron recently warned that we could be heading back to the dark ages where people die from what have been treatable diseases.
The reason for this gloomy prediction is the rise of antibiotic-resistant bugs.
In a world where we’re used to doctors being able to solve most of our ills, this is a truly terrifying prospect.
But at least in Sheffield we can be safe in the knowledge that the fight to save lives is firmly centred here, at its academic institutions and teaching hospitals.
It was in Sheffield in 1941 that the first clinical trials of penicillin took place and in the 21st century it is once again leading the fight to develop new treatments to save lives.
The Florian Institute at Sheffield University was set up to tackle drug-resistant organisms and to help develop the next generation of antibiotics. When answers are found it will be due , in no small part, to the efforts of researchers and students here.
Life-saving work goes on every day in our hospitals, with the diabetic foot care programme at the Norhern General Hospital featured today being just one example.