A Sheffield University spin-out that has developed a computer simulation which can be used to model how people might react to new pharmaceuticals has been presented with a Queen’s Award for Innovation.
Simcyp’s technology enables scientists developing new pharmaceuticals to analyse how a drug is absorbed, distributed, metabolised and excreted in virtual populations of patients, before carrying out clinical trials in humans.
The simulation allows researchers to predict how people from different demographic and genetic backgrounds, living in different environments and with diseases at different stages are likely to react to the new drug.
They can also predict the reaction in people who are already taking a cocktail of drugs for the condition. Simulations can also help with the design of human trials; minimising unnecessary drug exposure to human volunteers and animals, reducing costs and saving time during the development of the drug.
Simcyp’s award was presented on behalf of the Queen by the Lord Lieutenant of South Yorkshire, David Moody.